Biographies of Invited Speakers

PPXRD-5 is pleased to welcome the following Invited Speakers:

Dr. Simon Bates
Dr. William David
Irene Margiolaki
Dr. Colin R. Pulham
Dr. Andre Raw
Dr. Joseph H. Reibenspies
Dr. Raj Suryanarayanan


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Dr. Simon Bates
Simon Bates is a Research Fellow at SSCI Inc. and an Associate Adjunct Professor in Industrial Pharmacy at Purdue University. In 1985 He received his Ph.D. in Applied Physics from the University of Hull for his work on Neutron Diffraction of Magnetic Rare Earth Alloys. The Neutron Diffraction Measurements were performed at the Institute Laue Langevin (Grenoble). Upon graduation, he worked as a Fellow in the Department of Physics at Edinburgh University. In this capacity, he used x-ray diffraction and neutron diffraction measurements to study phase transitions in solid state materials. From 1988 to 2003, he worked in the Analytical X-ray equipment manufacturing and sales industry. His positions as Product Manager at Philips Analytical and later at Kratos (Shimadzu), as well as Vice President of Science at Bede Scientific resulted in new business development for X-ray diffraction and X-ray fluorescence. His recent move to SSCI has allowed him to develop new methods for the study of organic solid state materials using X-ray diffraction and to use his expertise in a variety of projects for the pharmaceutical community. He currently has over 50 publications on diffraction analysis of solid state materials.

Dr. William David
Rutherford Appleton Laboratory, Oxon, UK
Bill David is currently the ISIS Senior Fellow at the Rutherford Appleton Laboratory in the United Kingdom. His main areas of research interest are in the theoretical and experimental aspects of powder diffraction. He graduated with first class honours in Physics from the University of Oxford and completed his doctorate entitled "Structural phase transitions in ferroic ABO4 crystals" in 1981 under the supervision of Professor Mike Glazer. He then moved to the Inorganic Chemistry Laboratory in Oxford to work with Professor John Goodenough on the crystallography of lithium battery materials.

For the past 20 years, Bill has worked at the ISIS spallation neutron source at the Rutherford Appleton Laboratory. In 1983, he was responsible for building the high resolution time-of-flight powder diffractometer, HRPD, at ISIS and was HRPD instrument scientist until 1992. During that time he published a number of key structural papers in the area of powder diffraction including the first correct structures of the high temperature superconductor, YBa2Cu3O7, and the prototypic fullerene, C60. He was Group Leader of Crystallography at ISIS from 1987 to 1992 and since then has been ISIS Senior Research Fellow.

Over the past six years, Bill has worked closely with Dr Kenneth Shankland on the solution of crystal structures from powder data alone with a particular emphasis on pharmaceutical materials. Together with the Cambridge Crystallography Data Centre, they have developed the global optimisation structure solution program, DASH, which has now been used successfully in the solution of several hundred crystal structures.

Dr. Irene Margiolaki
European Synchrotron Radiation Facility (ESRF), Grenoble, France
Irene Margiolaki is a post-doctoral scientist at the ID31 high resolution powder diffraction beam line of the ESRF . She has spent part of her studies ( Department of Physics, Univ. of Crete, Greece- 1999) in the Polymer Science Group at the Institute of Electronic Structure and Laser Foundation (FORTH, Crete, Greece). Her DPhil research  (Univ. of Sussex, UK- 2004) was focused on the structural, electronic and superconducting properties of fullerene and boride solids using s ynchrotron X-ray powder diffraction, elastic and inelastic neutron scattering and muon positive spin relaxation t echniques. Her research interests are primarily in the area of crystallography, using powder diffraction to solve and refine the crystal structures of materials and compounds for which single crystals are unavailable. An important part of her current research activities are in methods development with a particular interest in exploiting the potential of protein powder diffraction and in exploring its complementarity with single crystal techniques; a field pioneered by R. B. Von Dreele and continued at ESRF with very promising results to date.

Dr. Colin R. Pulham
The University of Edinburgh, Edinburgh, U.K.
Colin Pulham studied Chemistry at the University of Oxford where he obtained a DPhil. and successfully synthesized and characterised the first uncoordinated gallium hydrides. After a further two years of research at Oxford , he moved to the University of Edinburgh where he is currently a senior lecturer in the School of Chemistry . His research interests include the study of the effects of pressure on molecular compounds such as pharmaceuticals and energetic materials, and this has led to the development of novel techniques for the exploration of polymorphism in molecular compounds. This has been illustrated by the discovery of new polymorphs and solvates of piracetam. Through an interest in crystal engineering, he recently prepared and structurally characterised a series of adducts of acetaminophen including the first hydrates.

He also has a strong interest in promoting public awareness of science and was recently awarded the Royal Society Kohn Award for Excellence in Engaging the Public with Science Communication.

Dr. Andre Raw
Andre Raw received his B.S. degree in chemistry from the Massachusetts Institute of Technology (1988) and his Ph.D. degree in organic chemistry from the University of California at Berkeley (1993). He was a post-doctoral research fellow with Alfred G. Gilman at the University of Texas Southwestern Medical Center (1994-1998) where his interests focused on protein biochemistry and X-ray crystallography. Upon completing his post-doctoral training, Dr. Raw took a position as a principle investigator at the Agricultural Research Service (1998-2000) where his research focus involved the rational design of molecules that alter arthropod behavior, as well as the isolation and characterization of their requisite protein receptors. In 2000, Dr. Raw joined the Food and Drug Administration (FDA) and is currently in the Office of Science and Regulatory Policy for the Office of Generic Drugs. He is involved in the review and resolution of complex scientific and regulatory issues in generic drug applications, citizen petitions, and industry correspondence.

Dr. Joseph H. Reibenspies
Texas A&M University, College Station, Texas, U.S.A.
I received my Ph.D. in chemistry from Colorado State University under the guidance of Professor Oren Anderson. I established the Single-crystal X-ray Diffraction Laboratory for Texas A & M University, Department of Chemistry in 1987 and the X-ray powder diffraction laboratory in 1999. In 2001 the two laboratories were combined to form the X-ray Diffraction Laboratory and I was assigned as its manager.

Raj Suryanarayanan (Sury)
Raj Suryanarayanan (Sury) is Morse Alumni Distinguished Professor of Pharmaceutics in the College of Pharmacy , University of Minnesota . He obtained his Ph.D. degree in Pharmaceutics from University of British Columbia , Vancouver , Canada . His research is focused in the area of solid-state properties of drugs. His publications in this field deal with phase transitions in solids, implications of in situ phase transitions on product performance, evaluation of concepts of crystallinity and development of new techniques to evaluate crystallinity in solids. He has developed X-ray diffractometric techniques for the qualitative and quantitative analyses of solid phases, to determine the drug content in intact tablets and to study solid-state reactions. His research group is currently involved in developing low temperature powder X-ray diffractometric techniques to study frozen and freeze-dried pharmaceutical systems. He is a consultant to numerous pharmaceutical companies and has served as a member of the USP Expert Committee (Excipients test methods). He is a fellow of the AAPS and is the past-chair of the Teachers of Pharmaceutics Section of the American Association of Colleges of Pharmacy.

 

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Information on Past PPXRD Symposiums
PPXRD-4, February 21-24, 2005
PPXRD-3, February 23-25, 2004
PPXRD-2, December 9-12, 2002
PPXRD-1 - September 27-29, 1999

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