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PPXRD-8

The International Centre for Diffraction Data is pleased to announce The 8th Pharmaceutical Powder X-ray Diffraction Symposium in Glasgow, Scotland, U.K..

Bios of Invited Speakers:

Dr. Angela Altomare was born in Bari, Italy, in 1963. She is married with two sons. In 1988 she graduated cum laude in Physics at the University of Bari. Since 1988, she has worked as researcher (firstly by term contracts and then, from 2001, in permanent position) at the Institute of Crystallography of the Italian National Research Council in Bari. Since 2006 she is Senior Researcher. Her research activity has been carried out in collaboration with Prof. Carmelo Giacovazzo, scientist of great renown in Crystallography. In 1999, she received from the Italian Association of Crystallography the AIC prize for ‘The Activity and The Original and Innovative Research Results in the Field of Crystallographic Methodologies, either Theoretical or Applicative and for the Work on the Association Activities’. Dr. Altomare research activity has been referenced in more than 70 scientific publications in important international reviews, several communications at national and international conferences, participations (as invited and chairman also) at congresses and schools. Dr. Altomare is co-author of eight important crystallographic computing programs widely used by the national and international community aimed at: ab-initio structure solution by single crystal data (SIR92 and SIR97), extraction of the integrated intensities from a powder diffraction pattern (EXTRA), ab-initio structure solution by powder diffraction data (SIRPOW92, EXPO and EXPO2004), qualitative (QUALX) and quantitative (QUANTO) analysis of multiphase mixtures. She has been referee for Acta Crystallographica, Journal of Applied Crystallography, Zeitschrift fur Kristallographie and Journal of Physical Chemistry. Her research activity is mainly devoted to the development of innovative methodologies aimed at improving the ab-initio structure solution process by powder diffraction data of organic and inorganic compounds. Some of her scientific interests are: Space Group Determination, Direct Methods, Patterson Methods, Direct Space Methods, Pattern Decomposition, Structure Model Optimization.

Eyal Barash is Chief Patent Counsel to Aptuit, Inc. and an affiliate with Aptuit Consulting.  Mr. Barash specializes in intellectual property aspects of solid forms including cocrystals, polymorphs, disordered solids and drug delivery.  He has been invited to deliver lectures throughout the world on these issues and how to use the latest scientific advances in  the solid state to advance meaningful lifecycle management strategies.  Mr. Barash is a member of the American Chemical Society, the American Association of Pharmaceutical Scientists where until recently he served as the chair of the Intellectual Property Focus Group, the American Intellectual Property Law Association, and the American Bar Association.
 
Mr. Barash holds a B.S. in chemistry and a B.A. in history from Indiana University, an M.S. degree in physical chemistry from the University of California at Berkeley and a J.D. from Northwestern University.  Prior to joining Aptuit, Mr. Barash was in private practice in Washington, D.C where his practice specialized in solid-form patent prosecution, counseling and litigation.

Dr. Vincent Caron received his Ph.D in Material Sciences from the Université des Sciences et Technologies de Lille in France where he worked on mechanosynthesis and solid state vitrification of molecular alloys under the supervision of Dr. Jean-Francois Willart and Pr. Marc Descamps. His work involved characterization of pharmaceutics by Powder X-ray Diffraction, Thermal analysis and Nuclear Magnetic Resonance. In 2007, he went for a postdoctoral position at the University of Connecticut, U.S.A. in the laboratory of Dr. Michael J. Pikal where he studied relationship between molecular mobility and crystallization in mixtures of active pharmaceutical ingredients and excipients. He joined in September 2008 the School of Pharmacy of Trinity College Dublin as a Research Fellow in the framework of a Solid State Pharmaceutical Cluster where his work concerns the influence of processing on the physical state and the influence of physical state on processing of pharmaceutical compounds.

Dr. Timothy Fawcett began his career receiving his B.S. in Chemistry at the University of Massachusetts and a Ph.D. degree in Inorganic Chemistry at Rutgers University. At Rutgers he combined x-ray crystallography with various spectroscopy techniques to study amino acids, chromophores of metalloproteins, and cupruretic agents for Wilson's disease. He was hired into the x-ray diffraction laboratory of the Analytical Sciences Department of the Dow Chemical Company in Midland, Michigan. During the next 10 years, he worked in the x-ray diffraction laboratory performing a wide range of analyses of corrosion products, inorganic materials, advanced ceramics, catalysts, pharmaceuticals and polymers. He eventually managed the inorganic analysis laboratories in Analytical Sciences, that included XRD, XRF, NAA, AA, ICP, AES, CHN, IC and electrochemical analyses. He worked with a team of scientists that developed and patented the simultaneous DSC/XRD/MS instrument, which won an IR-100 award in 1987. From 1986 to 1988 he served on the Board of Directors for the ICDD. During the 1990's, Tim managed several new product development groups in advanced materials, electronics, coatings, dispersions, ceramics and automotive components for different business organizations within the Dow Chemical Company. He became an ICDD fellow in 2000 and joined the ICDD as Executive Director in 2001. During his career, Tim has authored 35 publications, been a frequent guest lecturer, and presented several papers and workshops at global X-ray conferences. Several of his publications have been incorporated in the book, Methods & Practices in X-ray Diffraction, published by the ICDD. As Executive Director of the ICDD he has directed and participated in the dramatic growth of the Powder Diffraction File to ~600,000 entries which is now used by scientists in over 100 countries. 

Dr. Igor Ivanisevic received a Ph.D. in Computer Science (Robotics) from the University of Wisconsin-Madison in 2000. He has been working for SSCI, a division of Aptuit Inc., since 2002, most recently as a Research Fellow in the Chemistry group. His research interests focus on computational methods used to analyze and model x-ray amorphous pharmaceutical systems.

Dr. Greg Haugstad is a senior technical staff member and director of the Characterization Facility (www.charfac.umn.edu), a core research facility in the Institute of Technology (college of physical sciences, engineering and mathematics) at the University of Minnesota. The CharFac is affiliated with the University’s Materials Research Science and Engineering Center (www.mrsec.umn.edu) and Industrial Partnership for Research in Interfacial and Materials Engineering (www.iprime.umn.edu).  Dr. Haugstad received his B.A. in physics from Gustavus Adolphus College and Ph.D. in physics from the University of Minnesota examining semiconductor metallization in situ with synchrotron radiation photoelectron spectroscopy. After postdoctoral research with DuPont in an NSF engineering research center, he joined the CharFac in 1994 focusing on scanning probe microscopy (SPM) and ion beam analysis. In 2000 he became CharFac director and in 2001 joined the graduate faculty of the Department of Chemical Engineering and Materials Science. His research thrusts include (i) contrast mechanisms and special methods in SPM, (ii) nanotribology, (iii) nanoscale structure and properties of soft matter (synthetic and biological) in special environments including variable humidity, temperature and aqueous media. He has over sixty publications and is frequently engaged in the preceding topics in the context of interdisciplinary symposia, industrial research collaborations and consulting, analytical services, and teaching. His teaching includes graduate, undergraduate, technical-college and industrially targeted courses in materials characterization.

Dr. Sally, officially Sarah, Price trained as a theoretical chemist at the University of Cambridge, specialising in deriving models of the forces between molecules from their wavefunctions.  She worked at the Universities of Chicago and Cambridge, before becoming a lecturer at University College London, where she is now a Professor applying computational chemistry to the organic solid state.  She was the Principal Investigator on a  Research Councils U.K. Basic Technology project, "Control and Prediction of the Organic Solid State", www.cposs.org.U.K. which developed the calculation of crystal energy landscapes and their interpretation by comparison with experimental polymorph screening results. For her work on the computational modelling of polymorphism, she was awarded the 2005 Royal Society of Chemistry Industrially-Sponsored award in Statistical Mechanics and Simulation.

Dr. Jonathan Wright works at the European Synchrotron Radiation Facility, where he is involved in a wide range of X-ray diffraction experiments. Jon started working in powder diffraction when he used neutrons to study spiral magnetic structures, during his PhD in Cambridge, U.K., and at the ISIS facility. He then went to Grenoble, France, for a post-doc at the high resolution powder diffraction beamline, where he started working with proteins as powders. Jon is also interested in finding ways to bridge the gap between powder and single crystal methods and has recently been working on software to process data from large numbers of micro-crystals.