12 Campus Blvd, Newtown Square, PA 19073, USA
(610) 325-9814
(610) 325-9823
PPXRD-16 – XRD Training for the Pharmaceutical Scientist!

PPXRD is designed to create a forum for the exchange of knowledge and cutting-edge ideas among those interested in the combined fields of XRD and pharmaceutical sciences. It typically includes a full-day workshop, followed by several important sessions focused on practical applications of X-ray analysis in the study of pharmaceutical materials. Topics include patent and regulatory issues, formulation, product development, drug delivery, polymorphs, amorphous and nanomaterials, complimentary techniques, and much more.

Since 1999, ICDD has hosted 15 PPXRDs in various parts of the world. The host locations typically rotate and symposiums have been held in USA, Europe, and Asia. The abstracts from previous symposiums are publicly available as well as the presentations, except for the most recent event. The most recent presentations are available to attendees of that year’s event, for one year. After that time, they also  become publically available.

Looking for PPXRD Abstracts & Presentations?

Scenes from recent PPXRD in Hyderabad, India and Florida, USA.

Info on SPS-XRPD –  Spring Pharmaceutical Synchrotron
X-ray Powder Diffraction Workshop
Check out the Case Studies Opportunity!

Spring Pharmaceutical Synchrotron X-ray Powder Diffraction Workshop

Laboratory powder diffraction is a proven and trusted technique for pharma R&D but synchrotron powder diffraction pushes beyond the capabilities of conventional instrumentation. SPS-XRPD is joining with PPXRD to highlight the most exciting recent developments and opportunities in pharmaceutical R&D made possible by synchrotron XRPD. The joint meeting offers the chance to engage an active network of synchrotron, academic and industrial pharmaceutical scientists, promote awareness of this technique and lower the barriers to access synchrotron XRPD and total scattering techniques.

Visit the SPS-XRPD-1 website to view information from the first workshop held at Purdue University in May 2018.

Organizing Committee

Dr. Fabia Gozzo
Excelsus Structural Solutions (Swiss) AG, Switzerland
Prof. Stephen R. Byrn
Department of Industrial and Physical Pharmacy, Purdue University, USA
Dr. Chris J. Benmore
Advanced Photon Source, Argonne National Laboratory, USA
Mr. Stefan Müller
Paul Scherrer Institute, Switzerland
Dr. Benno Rechsteiner
Park Innovaare, Switzerland
Dr. Mathilde Reinle-Schmitt
Excelsus Structural Solutions (Swiss) AG, Switzerland
Dr. Pamela A. Smith
Improved Pharma, USA

Contact: sps-xrpd@excels.us

Case Studies Program

In conjunction with the upcoming joint PPXRD-16/SPS-XRPD-2 meeting taking place from the 9th to the 12th May 2019 in Switzerland, Excelsus Structural Solutions launches a program of ‘case studies’. This program gives 5 selected pharmaceutical companies the opportunity to explore for free the capabilities offered by Synchrotron XRPD on a real industrial problem. Examples include purity assessment of APIs or formulations, trace analyses, quantitative phase analysis, amorphous quantification. The results would then be presented in a dedicated session of the conference and act as sources of inspiration to nurture new and innovative ideas based around the unique potential of Synchrotron X-ray Powder Diffraction. More details about the company and the program are available in the attached brochure. Excelsus’ team looks forward to receiving your short application for the case studies program before November 15th 2018!  Think outside the box and challenge us!

For questions or assistance regarding the Case Studies Program, please contact:

Mathilde Reinle-Schmitt, PhD,  Scientist
Excelsus Structural Solutions (Swiss) AG
+41 563104470
+33616735985
m.reinle-schmitt@excels.us
www.excelsusSS.com
PARK innovAARE, 5234 Villigen – Switzerland

PPXRD Information

Dr. Tom Blanton, Chair, International Centre for Diffraction Data, Newtown Square, PA, USA

Dr. Detlef Beckers, PANalytical, Almelo, The Netherlands

Dr. Graciela C.D. de Delgado, University de Los Andes, Merida, Venezuela

Dr. Julien Giovannini, AstraZeneca R&D, Sweden

Dr. Fabia Gozzo, Excelsus Structural Solutions sprl, Brussels, Belgium

Dr. Arnt Kern, Bruker AXS GmbH, Karlsruhe, Germany

Ms. Terry Maguire, International Centre for Diffraction Data, Newtown Square, PA, USA

Dr. Keisuke Saito, Rigaku Americas, Houston, TX, USA

Dr. Gregory A. Stephenson, Crystal Pharmatech Inc., Fishers, IN, USA

Dr. Raj Suryanarayanan, University of Minnesota, Minneapolis, MN, USA

Dr. Shawn Yin, Bristol-Myers Squibb Company, New Brunswick, NJ, USA

 

Local Organizer for PPXRD-15
Professor T. N. Guru Row, Indian Institute of Science, India

 

Biographies of Organizing Committee

Dr. Thomas Blanton – PPXRD Chair
International Centre for Diffraction Data, Newtown Square, PA, USA

Tom is the Executive Director and Principal Scientist at ICDD. Before joining ICDD he was a Senior Principal Scientist at Eastman Kodak Company where he worked in industrial applications of X-ray diffraction and X-ray fluorescence for 31 years. He was responsible for the operation of the X-ray Spectroscopy Laboratory, utilizing diffractometers for powder, pole figure, nonambient, high-resolution, reflectivity, and two-dimensional XRD. Materials analyzed included inorganics, organics, solid state devices, thin films, corrosion products, ceramics, pharmaceuticals, polymers, and nanomaterials. Tom was also the Technical Leader in the Specialty Materials Development Laboratory. His area of focus was utilization of XRD for microstructure characterization resulting in new materials development for intellectual property and product development. Tom has 180+ publications including 4 book chapters, 46 U.S. Patents and 57 international patents.

Tom has served as a member of the ICDD Board of Directors for the terms 1992-1998 and 2004-2013, serving as Chairman 2008-2012. He has also received the honor of being named an ICDD Distinguished Fellow. Tom has been an instructor at the SUNY Albany and ICDD XRD Clinics for more than 30 years, and has served as a lecturer at the University of Rochester.

Dr. Detlef Beckers
PANalytical, Almelo, The Netherlands
Lead Scientist

Ph.D. in Physics at the Research Center Jülich, Solid State Physics Institute, Germany in 1996.

Dr. Beckers joined PANalytical B.V. in 1996 (Philips Analytical B.V. at that time) in the position of Project Manager XRD (X-ray diffraction). He was responsible for the management of hardware development projects and (pre-) development of new optical XRD modules. He then assumed the position of Market Segment Manager Pharmaceuticals, Food and Life Science where he was responsible for applications and business development, and the co-ordination of the pharmaceutical, food and life science market activities within the company. Today, he serves as Lead Scientist for PANalytical.

Dr. Graciela C.D. de Delgado, University de Los Andes, Merida, Venezuela

Bio coming soon

Dr. Julien Giovannini
AstraZeneca, Sweden

Bio coming soon

Dr. Fabia Gozzo
Excelsus Structural Solutions sprl, Brussels, Belgium

Bio coming soon

Dr. Arnt Kern
Bruker AXS GmbH, Karlsruhe, Germany

Bio coming soon

Dr. Keisuke Saito 
Rigaku, Houston, TX, USA

Dr. Saito earned his Ph.D. in Material Science at Tokyo Institute of Technology, Tokyo, in 2002. He joined Rigaku in 2011, and has been in charge of product management of X-ray diffractometers and global marketing

Dr. Gregory A. Stephenson
Crystal Pharmatech Inc., Fishers, IN, USA
Senior Scientific Advisor

Dr. Greg Stephenson received his Ph.D. degree in Medicinal Chemistry from Purdue University where he conducted his graduate research under the advisement of Professor Stephen Byrn. In 1994, he joined Eli Lilly and Company’s Preformulation Department where he is a Research Advisor responsible for the discovery and characterization of salts and polymorphic forms of potential drug substances.  Much of his work centers around the application of solid state techniques such as Single Crystal and Powder X-ray Diffraction and 13C solid-state NMR spectroscopy, to better understand physical properties of pharmaceuticals. Greg has published over 60 peer-reviewed research articles and patents, serves as Associate Editor for the Journal of Pharmaceutical Sciences, and is an elected Fellow for the ICDD.

Dr. Raj Suryanarayanan
University of Minnesota, Minneapolis, MN, USA
Professor and William and Mildred Peters Endowed Chair College of Pharmacy

Dr. Suryanarayanan (Sury) is a Professor of Pharmaceutics in the College of Pharmacy, University of Minnesota.  He also holds the William and Mildred Peters Endowed Chair in Pharmaceutics. He obtained his Bachelor of Pharmacy and Master of Pharmacy degrees from the Banaras Hindu University, Varanasi, India and M.Sc. and Ph.D. degrees in Pharmaceutics from the University of British Columbia, Vancouver, Canada. His research is focused in the area of solid-state properties of drugs.  His publications in this field deal with phase transitions in solids, implications of in situ phase transitions on product performance, evaluation of concepts of crystallinity and development of new techniques to evaluate crystallinity in solids.  He has developed X-ray diffractometric techniques for the qualitative and quantitative analyses of solid phases, to determine the drug content in intact tablets and to study solid-state reactions.  His research group is currently involved in developing low temperature powder X-ray diffractometric techniques to study frozen and freeze-dried pharmaceutical systems.  He is a consultant to numerous pharmaceutical companies and has served as a member of the USP Expert Committee (excipients test methods). He is a fellow of the American Association of Pharmaceutical Scientists and is the past-chair of the Teachers of Pharmaceutics Section of the American Association of Colleges of Pharmacy.

 

Dr. Shawn (Xiaotian) Yin
Bristol-Myers Squibb Company, New Brunswick, NJ, USA
Principal Scientist
Solid-State Chemistry Group
Analytical Research & Development
Research & Development

Dr. Shawn (Xiaotian) Yin received his Ph. D. in Solid-State Chemistry from the University of Waterloo, Canada. He did his Post Doctoral fellowship at the Department of Materials Sciences and Engineering, Cornell University, U.S.  Currently, Dr. Yin is a Principal Scientist and the group leader of the Crystal Form Chemistry and Characterization group at Bristol-Myers Squibb. His research interests include pharmaceutical polymorphic form studies, pre-formulation work, nanomaterials for drug delivery, physical characterizations of pharmaceutical substances and powder X-ray diffraction applications in pharmaceutical sciences.

Dr. Yin has (co)-authored 15 scientific publications and eight patents.  He serves as a scientific organization committee member for the Pharmaceutical Powder X-ray Diffraction Symposium.  Dr. Yin is also a frequent invited lecturer at international and domestic scientific conferences and workshops.

PPXRD-15 – 18-20 August 2017
Hyderabad, India

PPXRD-15 Presentations are now available below. Previous years’ abstracts and presentations are available in the Research Tools Area.

Characterizing Biological Macromolecules using SAXS on a Multi-Purpose Laboratory X-ray Diffraction System D. Beckers, J. Bolze, B. Schierbeek, PANalytical, B.V., The Netherlands
A. Adibhatla, PANalytical, Inc., USA
Atomic Pair Distribution Function (PDF) and X-ray Scattering Methods to Assess Amorphous Organic Compounds D. Beckers, M. Gateshki, PANalytical B.V., The Netherlands
A. Adibhatla, PANalytical, Inc., USA
TEM 3D Precession Electron Diffraction Tomography to Solve Pharmaceutical API Structures P.P. Das, S. Nicolopoulos, NanoMEGAS sprl, Belgium
Fast PDF Screening of Amorphous Pharmaceuticals C. Drathen, A. Kern, M. Evans, Bruker AXS GmbH, Germany
Invited: Crystal Morphology Prediction of Structures Determined by X-ray Powder Diffraction F.F. Ferreira, Federal University of ABC (UFABC), Brazil
F. Punzo, Università degli Studi di Catania, Italy
The Appropriate Internal Standard for Pharmaceuticals: The Art of Dealing with Compromises

M.L. Reinle-Schmitt, R. Frison, Excelsus Structural Solutions (Swiss) AG, Switzerland
P.P. Mazzeo, Excelsus Structural Solutions (Swiss) AG, Switzerland and University of Parma, Italy
F. Gozzo, Excelsus Structural Solutions (Swiss) AG, Switzerland and Excelsus Structural Solutions sprl, Belgium
Invited: Why Polymorphism? An Evaluation using Experimental Charge Densities Analysis T.N. Guru Row, Indian Institute of Science, India
Lessons Learned from 25 Commercial Pharmaceutical Crystal Structure Prediction Studies J. van de Streek, M.A. Neumann, Avant-garde Materials Simulation, Germany

PPXRD-15 – 18-20 August 2017 – PPXRD-15 Program
Hyderabad, India

PPXRD-14 – 6-9 June 2016 – PPXRD-14 Program
Sanibel Harbour Marriott
Fort Myers, Florida, USA

PPXRD-13 – 18-21 May 2015 – PPXRD-13 Program
Schwarzwald Panorama
Bad Herrenalb, Germany

PPXRD-12 – 20-24 May 2013 – PPXRD-12 Program
Institute of Physics, Chinese Academy of Sciences
Beijing, China

PPXRD-11 – 15-18 May 2012 – PPXRD-11 Program
Sanibel Harbour Marriott Resort & Spa
Fort Myers, Florida, USA

PPXRD-10 – 16-19 May 2011 – PPXRD-10 Program
Lyon, France

PPXRD-9 – 22–25 February 2010 – PPXRD-9 Program
Hilton Head Island, South Carolina, USA

PPXRD-8 – 4-7 May 2009 – PPXRD-8 Program
Glasgow, Scotland, U.K

PPXRD-7 – 25-28 February 2008 – PPXRD-7 Program
Orlando, FL, U.S.A.

PPXRD-6 – 19-22 February 2007 – PPXRD-6 Program
Barcelona, Spain

PPXRD-5 – 14-16 February 2006 – PPXRD-5 Program
Somerset, New Jersey, USA

PPXRD-4 – 21-24 February 2005 – PPXRD-4 Program
Barcelona, Spain

PPXRD-3 – 23-25 February 2004 – PPXRD-3 Program
Hilton Head Island, South Carolina, USA

PPXRD-2 – 9-12 December 2002 – PPXRD-2 Program
Concordville, PA, USA

PPXRD-1 – 27-29 September 1999 – PPXRD-1 Program
Newtown Square, PA, USA

Twitter
Facebook
LinkedIn
Instagram
YouTube